Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.35 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6341117 | 0.98 | PTGS1 (0.54) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL6263592 | 0.88 | MAPT (0.52) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL6265531 | 0.86 | MAPT (0.50) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6354372 | 0.86 | MAPT (0.50) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL6261724 | 0.85 | MAPT (0.48) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6339551 | 0.85 | MAPT (0.48) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL6261482 | 0.85 | MAPT (0.48) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6339537 | 0.83 | MAPT (0.47) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| Hydrochloric Acid SCHEMBL6341118 | 0.83 | MAPT (0.47) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 | |
| SCHEMBL4768361 | 0.83 | PTGS1 (0.60) | PTGS1ALDH1A1MAPTSLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317426-B1 | BETA-THIO-AMINO ACIDS | GRUENENTHAL GMBH (DE) | 2005-11-16 | — | — | EP | claimed |
| US-6846843-B2 | Gabapentin; antiepileptic agents, analgesics | GRUENENTHAL GMBH (DE) | 2005-01-25 | — | — | US | claimed |
| US-20030236253-A1 | Beta-thioamino acids | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | claimed |
| EP-1317426-A1 | BETA-THIO-AMINO ACIDS | Grünenthal GmbH (DE) | 2003-06-11 | — | — | EP | claimed |
| WO-2002022568-A1 | ss-THIO-AMINO ACIDS | Grünenthal GmbH (DE) | 2002-03-21 | — | — | WO | claimed |
| EP-1317426-B1 | BETA-THIO-AMINO ACIDS | GRUENENTHAL GMBH (DE) | 2005-11-16 | — | — | EP | disclosed |
| US-6846843-B2 | Gabapentin; antiepileptic agents, analgesics | GRUENENTHAL GMBH (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20030236253-A1 | Beta-thioamino acids | GRUENENTHAL GMBH (DE) | 2003-12-25 | — | — | US | disclosed |
| EP-1317426-A1 | BETA-THIO-AMINO ACIDS | Grünenthal GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002022568-A1 | ss-THIO-AMINO ACIDS | Grünenthal GmbH (DE) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030236253-A1 | Beta-thioamino acids | TPMT, OPRD1, TST | PTGS1 47/4885ALDH1A1 428/4885MAPT 2042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.