Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13736974 | 0.94 | CYP1A2 (0.40) | CD38ALDH1A1HSPB1HPGDCYP1A2 | |
| SCHEMBL13737536 | 0.83 | LTA4H (0.59) | LTA4HPTGS1PTGS2ALDH1A1KMT2A | |
| SCHEMBL3386044 | 0.81 | ALDH1A1 (0.54) | LTA4HPTGS1PTGS2ALDH1A1HPGD | |
| SCHEMBL1641137 | 0.80 | LTA4H (0.61) | LTA4HPTGS1PTGS2ALDH1A1HSPB1 | |
| SCHEMBL13736543 | 0.79 | MAPT (0.49) | ALDH1A1HPGDCYP1A2CYP2C9KMT2A | |
| SCHEMBL6408582 | 0.79 | LTA4H (0.60) | LTA4HPTGS1PTGS2ALDH1A1MEN1 | |
| SCHEMBL13736214 | 0.79 | CD38 (0.42) | CD38LTA4HPTGS1PTGS2MEN1 | |
| SCHEMBL13737864 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1HPGDCYP1A2CYP2C9MEN1 | |
| SCHEMBL3382465 | 0.78 | ALDH1A1 (0.49) | LTA4HPTGS1PTGS2ALDH1A1HSPB1 | |
| SCHEMBL16973009 | 0.77 | LTA4H (0.46) | LTA4HPTGS1PTGS2ALDH1A1HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153154-A1 | OXETANE SUBSTITUTED THIENO PYRIMIDINONES | RICHTER GEDEON NYRT. (HU) | 2012-11-15 | — | — | WO | claimed |
| WO-2012153154-A1 | OXETANE SUBSTITUTED THIENO PYRIMIDINONES | RICHTER GEDEON NYRT. (HU) | 2012-11-15 | — | — | WO | disclosed |