Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 3/20 | 0.37 |
| ▸ | IGF1R | P08069 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571991 | 0.97 | GRIN1 (0.40) | MEN1KMT2ABCHEACHEMGAT2 | |
| SCHEMBL456750 | 0.94 | MEN1 (0.44) | MEN1KMT2ABCHEACHEALDH1A1 | |
| SCHEMBL29750185 | 0.94 | MEN1 (0.44) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Acetic Acid SCHEMBL20422024 | 0.93 | MEN1 (0.41) | MEN1KMT2ABCHEACHEMGAT2 | |
| Methane SCHEMBL13736906 | 0.93 | MEN1 (0.43) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Hydrochloric Acid SCHEMBL574759 | 0.93 | MEN1 (0.43) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Bromide SCHEMBL13737447 | 0.93 | MEN1 (0.43) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Succinic Acid SCHEMBL13739526 | 0.92 | FFAR1 (0.40) | MEN1KMT2AALDH1A1CYP1A2TSHR | |
| Trifluoroacetic Acid SCHEMBL4717787 | 0.90 | MEN1 (0.38) | MEN1KMT2AALDH1A1CYP1A2TSHR | |
| Cadaverine Tartrate SCHEMBL13736620 | 0.90 | MEN1 (0.40) | MEN1KMT2AALDH1A1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012153130-A1 | SALTS OF 4 -ETHYL-1-(2 - PHENYLETHYL) - 8 -PHENOXY - 2, 3 - DIHYDRO - 1H - PYRROLO [3, 2 -C] QUINOLINE AND THEIR USE FOR TREATING INFECTIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-11-15 | — | — | WO | disclosed |