Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | INSR | P06213 | 3/20 | 0.40 |
| ▸ | IGF1R | P08069 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750185 | 1.00 | MEN1 (0.44) | MEN1KMT2ABCHEACHEINSR | |
| Bromide SCHEMBL13737447 | 0.99 | MEN1 (0.43) | MEN1KMT2ABCHEACHEINSR | |
| Methane SCHEMBL13736906 | 0.99 | MEN1 (0.43) | MEN1KMT2ABCHEACHEINSR | |
| Hydrochloric Acid SCHEMBL574759 | 0.99 | MEN1 (0.43) | MEN1KMT2ABCHEACHEINSR | |
| Acetic Acid SCHEMBL20422024 | 0.95 | MEN1 (0.41) | MEN1KMT2ABCHEACHEINSR | |
| Sulfuric Acid SCHEMBL13737697 | 0.94 | MEN1 (0.40) | MEN1KMT2ABCHEACHEINSR | |
| SCHEMBL2546127 | 0.94 | KMT2A (0.48) | MEN1KMT2ABCHEACHEALDH1A1 | |
| Succinic Acid SCHEMBL13739526 | 0.93 | FFAR1 (0.40) | MEN1KMT2AALDH1A1CYP1A2TSHR | |
| SCHEMBL571991 | 0.93 | GRIN1 (0.40) | MEN1KMT2ABCHEACHEINSR | |
| Hydrochloric Acid SCHEMBL4184552 | 0.93 | KMT2A (0.47) | MEN1KMT2ABCHEACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4195924-B1 | DISINFECTANT COMPOSITION | HELPERBY THERAPEUTICS LTD (GB) | 2025-06-25 | — | — | EP | claimed |
| US-20230337671-A1 | DISINFECTANT COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2023-10-26 | — | — | US | claimed |
| EP-4195924-A1 | DISINFECTANT COMPOSITION | Helperby Therapeutics Limited (GB) | 2023-06-21 | — | — | EP | claimed |
| EP-2600868-B1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND AN AMINOGLYCODISE ANTIMICROBIAL AGENT | HELPERBY THERAPEUTICS LTD (GB) | 2022-03-09 | — | — | EP | claimed |
| WO-2022038351-A1 | DISINFECTANT COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2022-02-24 | — | — | WO | claimed |
| EP-3368031-B1 | TRIPLE COMBINATION COMPRISING 4-METHYL-8-PHENOXY-1-(2-PHENYLETHYL)-2,3-DIHYDRO-1H-PYRROLO[3,2-C]QUINOLINE, MUPIROCIN AND NEOMYCIN | HELPERBY THERAPEUTICS LTD (GB) | 2022-01-05 | — | — | EP | claimed |
| CN-108289878-B | Triple combination | 赫尔普百治疗有限公司 | 2021-08-17 | — | — | CN | claimed |
| EP-2600869-B1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND A BETA-LACTAM ANTIMICROBIAL AGENT, MUPIROCIN OR CHLORHEXIDINE | HELPERBY THERAPEUTICS LTD (GB) | 2020-09-23 | — | — | EP | claimed |
| US-10736888-B2 | Triple combination | HELPERBY THERAPEUTICS LIMITED (GB) | 2020-08-11 | — | — | US | claimed |
| US-20180311232-A1 | TRIPLE COMBINATION | HELPERBY THERAPEUTICS LIMITED (GB) | 2018-11-01 | — | — | US | claimed |
| WO-2012046078-A1 | NOVEL COMPOSITION | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-04-12 | — | — | WO | claimed |
| WO-2012017215-A1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND A BETA-LACTAM ANTIMICROBIAL AGENT, MUPIROCIN OR CHLORHEXIDINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-02-09 | — | — | WO | claimed |
| WO-2012017216-A1 | COMBINATION OF A PYRROLOQUINOLINE COMPOUND AND AN AMINOGLYCODISE ANTIMICROBIAL AGENT | HELPERBY THERAPEUTICS LIMITED (GB) | 2012-02-09 | — | — | WO | claimed |
| WO-2011121345-A1 | NOVEL COMBINATION AND USE | HELPERBY THERAPEUTICS LIMITED (GB) | 2011-10-06 | — | — | WO | claimed |
| US-20100093691-A1 | TOPICAL FORMULATIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2010-04-15 | — | — | US | claimed |
| EP-2086542-A1 | TOPICAL FORMULATIONS | Helperby Therapeutics Limited (GB) | 2009-08-12 | — | — | EP | claimed |
| US-20090137622-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | HELPERBY THERAPEUTICS LIMITED (GB) | 2009-05-28 | — | — | US | claimed |
| EP-1945211-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | Helperby Therapeutics Limited (GB) | 2008-07-23 | — | — | EP | claimed |
| WO-2008056151-A1 | TOPICAL FORMULATIONS | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-05-15 | — | — | WO | claimed |
| WO-2007054693-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | HELPERBY THERAPEUTICS LIMITED (GB) | 2007-05-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10736888-B2 | Triple combination | MCRS1, TLR3, CD14 | MEN1 202/4885KMT2A 1987/4885BCHE 1798/4885 |
| US-20180311232-A1 | TRIPLE COMBINATION | MCRS1, TLR3, CD14 | MEN1 202/4885KMT2A 1987/4885BCHE 1798/4885 |
| US-20090137622-A1 | USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS | LPO, ARG1, CTSL | MEN1 1394/4885KMT2A 2403/4885BCHE 1538/4885 |
| US-20100093691-A1 | TOPICAL FORMULATIONS | DPM1, SUCLG1, LSS | MEN1 2763/4885KMT2A 4302/4885BCHE 2400/4885 |
| US-20230337671-A1 | DISINFECTANT COMPOSITION | POLR1C, POLE3, AQP3 | MEN1 2270/4885KMT2A 433/4885BCHE 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.