Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SDHB | P21912 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13738533 | 0.90 | PTPN11 (0.42) | PTPN11 | |
| SCHEMBL13737903 | 0.88 | L3MBTL1 (0.42) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL13736534 | 0.88 | L3MBTL1 (0.44) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL13735852 | 0.87 | PTPN22 (0.45) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL13736229 | 0.86 | L3MBTL1 (0.44) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL15829196 | 0.83 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL13738088 | 0.82 | PTPN11 (0.48) | PTPN11LDHA | |
| SCHEMBL13739517 | 0.79 | PTPN22 (0.54) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL13738188 | 0.78 | PTPN11 (0.44) | ALDH1A1GLAHPGDTDP1L3MBTL1 | |
| SCHEMBL13738019 | 0.78 | PTPN11 (0.48) | ALDH1A1GLAHPGDTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103561573-A | Tyrosine phosphatases and their use in modulating the activity of enzymes involved in the pathology of Mycobacterium tuberculosis | UNIV INDIANA RES & TECH CORP | 2014-02-05 | — | — | CN | disclosed |
| WO-2012149048-A1 | TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF TO MODULATE THE ACTIVITY OF LYP | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2012149049-A1 | TYROSINE PHOSPHATASE INHIBITORS AND USES THEREOF TO MODULATE THE ACTIVITY OF ENZYMES INVOLVED IN THE PATHOLOGY OF MYCOBACTERIUM TUBERCULOSIS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2012-11-01 | — | — | WO | disclosed |