Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969665 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL13739869 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL13739368 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL27630456 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL10434829 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL9715200 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL3826240 | 1.00 | ADRB2 (0.61) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL7638760 | 0.98 | ADRB2 (0.63) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL34465293 | 0.98 | ADRB2 (0.63) | ADRB2KDM4EHTR7TP53MAPK1 | |
| SCHEMBL9851280 | 0.93 | KDM4E (0.55) | ADRB2KDM4EHTR7TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681179-B1 | ORTHO-PHENYLPHENOL COMPOUNDS USEFUL AS HYDROCARBON MARKERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-04 | — | — | EP | disclosed |
| EP-2707471-B1 | ORTHO-PHENYLPHENOL COMPOUNDS AS MARKERS FOR HYDROCARBONS AND OTHER FUELS AND OILS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-9079838-B2 | Ortho-phenylphenol compounds | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-07-14 | — | — | US | disclosed |
| US-8961624-B2 | Ortho-phenylphenol compounds as markers for liquid hydrocarbons and other fuels and oils | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140075829-A1 | ORTHO-PHENYLPHENOL COMPOUNDS AS MARKERS FOR LIQUID HYDROCARBONS AND OTHER FUELS AND OILS | ANGUS CHEMICAL COMPANY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140081051-A1 | ORTHO-PHENYLPHENOL COMPOUNDS | ANGUS CHEMICAL COMPANY (US) | 2014-03-20 | — | — | US | disclosed |
| EP-2707471-A1 | ORTHO- PHENYLPHENOL COMPOUNDS AS MARKERS FOR HYDROCARBONS AND OTHER FUELS AND OILS | ANGUS Chemical Company (US) | 2014-03-19 | — | — | EP | disclosed |
| EP-2681179-A1 | ORTHO - PHENYLPHENOL COMPOUNDS USEFUL AS HYDROCARBON MARKERS | ANGUS Chemical Company (US) | 2014-01-08 | — | — | EP | disclosed |
| WO-2012154646-A1 | ORTHO- PHENYLPHENOL COMPOUNDS AS MARKERS FOR HYDROCARBONS AND OTHER FUELS AND OILS | ANGUS CHEMICAL COMPANY (US) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012154668-A1 | ORTHO - PHENYLPHENOL COMPOUNDS USEFUL AS HYDROCARBON MARKERS | ANGUS CHEMICAL COMPANY (US) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140081051-A1 | ORTHO-PHENYLPHENOL COMPOUNDS | APOL1, OSBPL3, CCNL2 | ADRB2 409/4885KDM4E 3345/4885HTR7 1553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.