SCHEMBL13740314

SCHEMBL13740314

OC(Cl)(C(Cl)(Cl)Cl)C(Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.50
LMNA P02545 2/20 0.33
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2E1 P05181 1/20 0.33
MAPK1 P28482 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL423019 0.75
SCHEMBL5705555 0.72
SCHEMBL23105 0.72
SCHEMBL16969844 0.72
SCHEMBL1686774 0.71 THRB (0.46) THRBLMNATSHRALDH1A1CYP2E1
SCHEMBL5525063 0.71
SCHEMBL23328059 0.67
SCHEMBL11335189 0.67
Chlorobutanol SCHEMBL5719643 0.67 THRB (1.00) THRBLMNATSHRALDH1A1
SCHEMBL566804 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707483-B1 METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION RWTH AACHEN UNIV (DE) 2017-10-18 EP disclosed
CN-106715539-A Modified solid polyalkylaluminoxane and catalyst for olefin oligomerization 住友化学株式会社 2017-05-24 CN disclosed
EP-2707483-A1 METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION BASF SE (DE) 2014-03-19 EP disclosed
US-20120295311-A1 Methods and Materials for Nucleic Acid Manipulation BASF SE (DE) 2012-11-22 US disclosed
WO-2012152691-A1 METHODS AND MATERIALS FOR NUCLEIC ACID MANIPULATION BASF SE (DE) 2012-11-15 WO disclosed