⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456061 | 0.80 | — | — | |
| SCHEMBL13740314 | 0.75 | THRB (0.50) | — | |
| SCHEMBL423173 | 0.75 | THRB (0.40) | — | |
| SCHEMBL16969844 | 0.72 | — | — | |
| SCHEMBL5705555 | 0.72 | — | — | |
| SCHEMBL23105 | 0.72 | — | — | |
| SCHEMBL418794 | 0.71 | THRB (0.38) | — | |
| SCHEMBL5525063 | 0.71 | — | — | |
| SCHEMBL1686774 | 0.71 | THRB (0.46) | — | |
| SCHEMBL5607954 | 0.69 | THRB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 528 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118159541-A | Gonadotropin releasing hormone antagonist and preparation method and application thereof | 山东绿叶制药有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| WO-2023246872-A1 | HETEROCYCLIC COMPOUND AS TAAR1 LIGAND AGONIST | 山东绿叶制药有限公司 | 2023-12-28 | — | — | WO | claimed |
| CN-115232129-B | PARP1 selective inhibitor and preparation method and application thereof | 上海闻耐医药科技有限公司 | 2023-12-01 | — | — | CN | claimed |
| WO-2023104178-A1 | PROTEIN KINASE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 山东绿叶制药有限公司 | 2023-06-15 | — | — | WO | claimed |
| WO-2023072284-A1 | GONADOTROPIN-RELEASING HORMONE ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东绿叶制药有限公司 | 2023-05-04 | — | — | WO | claimed |
| CN-115232129-A | PARP1 selective inhibitor and preparation method and application thereof | 上海闻耐医药科技有限公司 | 2022-10-25 | — | — | CN | claimed |
| EP-0302366-B1 | Substituted pyridine derivatives | BAYER AG (DE) | 1994-09-14 | — | — | EP | claimed |
| EP-0392241-B1 | SUBSTITUTED 1-ARYLPYRAZOLS | BAYER AG (DE) | 1993-06-02 | — | — | EP | claimed |
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | claimed |
| US-4747867-A | 1-aryl-4-cyano-5-halogenopyrazoles, composition containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | claimed |
| US-4740231-A | 1-aryl-5-alkoximinoalkylamino-pyrazoles, composition containing them, herbicidal and plant-growth regulating method of using them, and intermediates in the preparation of them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | claimed |
| US-4734125-A | 5-acylamido-1-aryl-pyrazoles, composition containing them and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | claimed |
| US-4711658-A | 5-perfluoroacylamino-4-nitro-1-arylpyrazole salts, plant growth regulating and herbicidal composition containing them, and plant growth regulating and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | claimed |
| US-4695308-A | Herbicidal substituted 5-amino-1-aryl-pyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | claimed |
| US-4685957-A | PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | claimed |
| US-4685956-A | 1-aryl-5-hydrazino-pyrazoles, compositions containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-08-11 | — | — | US | claimed |
| US-4681618-A | 1-aryl-5-halo-4-nitopyrazoles, herbicidal compositions containing them, and herbicidal method of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1987-07-21 | — | — | US | claimed |
| US-4614534-A | HERBICIDES, PLANT GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | claimed |
| US-4614533-A | Herbicidal 5-amino-1-phenylpyrazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | claimed |