SCHEMBL1374043

SCHEMBL1374043

C[C@H](N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 6/20 0.47
OPRM1 P35372 4/20 0.47
OPRK1 P41145 2/20 0.47
NPY4R P50391 7/20 0.46
NPY1R P25929 5/20 0.46
NPY2R P49146 4/20 0.46
NPY5R Q15761 3/20 0.46
IL1RN P18510 1/20 0.46
ERAP2 Q6P179 1/20 0.46
NAALAD2 Q9Y3Q0 1/20 0.45
APC P25054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370963 1.00 OPRD1 (0.47) OPRD1OPRM1OPRK1NPY4RNPY1R
SCHEMBL1374034 0.94 NAALAD2 (0.52) OPRD1OPRM1OPRK1NPY4RNPY1R
SCHEMBL1370956 0.94 NAALAD2 (0.52) OPRD1OPRM1OPRK1NPY4RNPY1R
SCHEMBL29531333 0.90 OPRD1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL15328626 0.90 OPRD1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL15328632 0.90 OPRD1 (0.55) OPRD1OPRM1OPRK1
SCHEMBL30931573 0.87 OPRD1 (0.53) OPRD1OPRM1OPRK1NPY4RNPY1R
SCHEMBL29707530 0.87 CHRND (0.47) NPY4RNPY1RNPY2RNPY5RNAALAD2
SCHEMBL30468670 0.87 CHRND (0.47) NPY4RNPY1RNPY2RNPY5RNAALAD2
SCHEMBL30578452 0.87 OPRD1 (0.50) OPRD1OPRM1OPRK1NPY4RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC (CA) 2016-09-15 US disclosed
EP-2794663-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF Angiochem Inc. (CA) 2014-10-29 EP disclosed
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2011-11-24 US disclosed
WO-2010063124-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF ANGIOCHEM INC. (CA) 2010-06-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160263235-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885
US-20110288011-A1 PEPTIDE THERAPEUTIC CONJUGATES AND USES THEREOF VIP, SLC1A5, SLC47A1 OPRD1 4036/4885OPRM1 3822/4885OPRK1 3911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.