Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531333 | 1.00 | OPRD1 (0.55) | OPRD1OPRM1OPRK1CTSLMME | |
| SCHEMBL15328632 | 1.00 | OPRD1 (0.55) | OPRD1OPRM1OPRK1CTSLMME | |
| SCHEMBL1374034 | 0.92 | NAALAD2 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL1370956 | 0.92 | NAALAD2 (0.52) | OPRD1OPRM1OPRK1 | |
| SCHEMBL1370963 | 0.90 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL1374043 | 0.90 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL7588968 | 0.89 | CTRB1 (0.57) | OPRD1OPRM1OPRK1CTSLMME | |
| SCHEMBL2544516 | 0.89 | CTRB1 (0.57) | OPRD1OPRM1OPRK1CTSLMME | |
| SCHEMBL29406594 | 0.89 | OPRD1 (0.52) | OPRD1OPRM1OPRK1CTSLMME | |
| SCHEMBL29351019 | 0.88 | OPRD1 (0.61) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122363-A2 | METHODS OF TREATING SMALL CELL LUNG CANCER | Evergreen Discovery, LLC (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20250186634-A1 | METHODS OF TREATING SMALL CELL LUNG CANCER | Evergreen Discovery, LLC (US) | 2025-06-12 | — | — | US | disclosed |
| EP-4554607-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | Rhythm Pharmaceuticals, Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015880-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-9169295-B2 | Macrocycles and macrocycle stabilized peptides | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |
| EP-2627662-B1 | METHODS FOR PREPARING MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL MYERS SQUIBB CO (US) | 2015-09-16 | — | — | EP | disclosed |
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281657-A1 | MACROCYCLES AND MACROCYCLE STABILIZED PEPTIDES | PTMS, VIP, MTPN | OPRD1 4530/4885OPRM1 4478/4885OPRK1 4371/4885 |
| US-20250186634-A1 | METHODS OF TREATING SMALL CELL LUNG CANCER | SSTR2, CCKBR, GRPR | OPRD1 1567/4885OPRM1 1273/4885OPRK1 1662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.