Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740507 | 1.00 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL19932524 | 1.00 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL6457893 | 0.80 | — | — | |
| SCHEMBL12601191 | 0.75 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL19781288 | 0.75 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL2562394 | 0.75 | — | — | |
| SCHEMBL22579511 | 0.75 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL2881411 | 0.75 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL14479600 | 0.73 | PARP1 (0.34) | — | |
| SCHEMBL12324791 | 0.73 | PARP1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2023-05-11 | — | — | US | disclosed |
| EP-2707035-B1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS-CYCLOOCTENE DIENOPHILE AND A DIENE | TAGWORKS PHARMACEUTICALS B V (NL) | 2020-04-01 | — | — | EP | disclosed |
| EP-2707035-B1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS-CYCLOOCTENE DIENOPHILE AND A DIENE | TAGWORKS PHARMACEUTICALS B V (NL) | 2020-04-01 | — | — | EP | disclosed |
| US-20190247513-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2019-08-15 | — | — | US | disclosed |
| US-9913921-B2 | Pretargeting kit for imaging or therapy comprising a trans-cyclooctene dienophile and a diene | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2018-03-13 | — | — | US | disclosed |
| US-9913921-B2 | Pretargeting kit for imaging or therapy comprising a trans-cyclooctene dienophile and a diene | TAGWORKS PHARMACEUTICALS B.V. (NL) | 2018-03-13 | — | — | US | disclosed |
| US-20160151505-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS N.V. (NL) | 2016-06-02 | — | — | US | disclosed |
| EP-2707035-A1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS - CYCLOOCTENE DIENOPHILE AND A DIENE | Koninklijke Philips N.V. (NL) | 2014-03-19 | — | — | EP | disclosed |
| WO-2012156920-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-22 | — | — | WO | disclosed |
| WO-2012153254-A1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS - CYCLOOCTENE DIENOPHILE AND A DIENE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-15 | — | — | WO | disclosed |
| WO-2012153254-A1 | PRETARGETING KIT FOR IMAGING OR THERAPY COMPRISING A TRANS - CYCLOOCTENE DIENOPHILE AND A DIENE | KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) | 2012-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247513-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | KIT, TPSB2, BTD | ALDH1A1 744/4885 |
| US-20230144534-A1 | CLEAVABLE TETRAZINE USED IN BIO-ORTHOGONAL DRUG ACTIVATION | KIT, TPSB2, BTD | ALDH1A1 760/4885 |
| US-20160151505-A1 | BIO-ORTHOGONAL DRUG ACTIVATION | JMJD7, KIT, PAICS | ALDH1A1 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.