SCHEMBL1374066

SCHEMBL1374066

COc1ccc(C(=O)CC(C)=O)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
HSD17B10 Q99714 2/20 0.64
LMNA P02545 1/20 0.64
ALOX15 P16050 1/20 0.64
APEX1 P27695 1/20 0.64
MAPK1 P28482 1/20 0.64
RECQL P46063 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
HDAC3 O15379 2/20 0.63
HDAC4 P56524 2/20 0.63
HDAC1 Q13547 2/20 0.63
HDAC7 Q8WUI4 2/20 0.63
HDAC2 Q92769 2/20 0.63
HDAC10 Q969S8 2/20 0.63
HDAC11 Q96DB2 2/20 0.63
HDAC8 Q9BY41 2/20 0.63
HDAC6 Q9UBN7 2/20 0.63
HDAC9 Q9UKV0 2/20 0.63
HDAC5 Q9UQL6 2/20 0.63
GSK3B P49841 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11136993 0.94 ALDH1A1 (0.58) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL153386 0.90 ALDH1A1 (0.76) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL29242089 0.87 NPC1 (0.60) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL29219054 0.86 ALDH1A1 (0.66) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL2003577 0.85 KMT2A (0.52) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL6050796 0.85 ALDH1A1 (0.60) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL2427418 0.84 PDE4B (0.66) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL628796 0.84 CA1 (0.59) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL17295084 0.84 ALDH1A1 (0.64) ALDH1A1HSD17B10LMNAALOX15APEX1
SCHEMBL1398724 0.84 ALDH1A1 (0.64) ALDH1A1HSD17B10LMNAALOX15APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116924899-B Synthesis method of natural equivalent raspberry ketone 复旦大学 2025-05-27 CN claimed
CN-116924899-A Synthesis method of natural equivalent raspberry ketone 复旦大学 2023-10-24 CN claimed
CN-116482246-A Method for rapidly determining aroma substances in ageing of white spirit 山西杏花村汾酒厂股份有限公司 2023-07-25 CN claimed
CN-112142642-B Preparation method of 1,2, 3-trisubstituted-5-trifluoromethyl pyrrole derivative 华侨大学 2022-03-04 CN claimed
CN-109970770-B Preparation method and application of Schiff base complex of binuclear copper 陕西理工大学 2021-05-25 CN claimed
CN-112142642-A Preparation method of 1,2, 3-trisubstituted-5-trifluoromethyl pyrrole derivative 华侨大学 2020-12-29 CN claimed
CN-117980454-B Aldehyde composition 三菱瓦斯化学株式会社 2026-05-19 CN disclosed
US-12570771-B2 Curing catalyst used for curing of polymer, production method for said curing catalyst, mositure-curable composition, and production method for cured product NITTO KASEI CO., LTD. (JP) 2026-03-10 US disclosed
EP-4682204-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2026-01-21 EP disclosed
US-12516157-B2 Curing catalyst used for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2026-01-06 US disclosed
EP-4656672-A1 METHOD FOR PRODUCING CURABLE COMPOSITION Kaneka Corporation (JP) 2025-12-03 EP disclosed
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
EP-4174052-B1 CURING CATALYST USED FOR CURING OF POLYMER, PRODUCTION METHOD FOR SAID CURING CATALYST, MOISTURE-CURABLE COMPOSITION, AND PRODUCTION METHOD FOR CURED PRODUCT NITTO KASEI CO LTD (JP) 2025-11-26 EP disclosed
US-4560691-A 5-(Phenyl)-1,6-naphthyridin-2(1H)-ones, their cardiotonic use and preparation STERLING DRUG INC. (US) 1985-12-24 US disclosed
US-4212806-A ANTIINFLAMMATORY, ANTIPYRETIC, ANALGESIC, ANTIDEPRESSANT GRUPPO LEPETIT S.P.A. (IT) 1980-07-15 US disclosed
US-4211708-A ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS GRUPPO LEPETIT S.P.A. (IT) 1980-07-08 US disclosed
US-4211709-A ANTIINFLAMMATORY AGENTS, CENTRAL NERVOUS SYSTEM DEPRESSANTS GRUPPO LEPETIT S.P.A. (IT) 1980-07-08 US disclosed
US-4198502-A ANTIINFLAMMATORY AGENT, CNS DEPRESSANTS, ANALGESICS, ANTIPYRETICS, ANTIULCER AGENTS GRUPPO LEPETIT S.P.A. (IT) 1980-04-15 US disclosed
US-4140696-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS AND CNS DEPRESSANTS GRUPPO LEPETIT S.P.A. (IT) 1979-02-20 US disclosed
US-3994869-A Photodegradable polyolefins containing aryl-substituted 1,3-diones ICI UNITED STATES INC. (US) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570771-B2 Curing catalyst used for curing of polymer, production method for said curing catalyst, mositure-curable composition, and production method for cured product RPS6KB1, RPS6KA1, RPS6KB2 ALDH1A1 851/4885HSD17B10 1017/4885LMNA 1968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.