Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.40 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626619 | 0.83 | DPP4 (0.41) | DPP4DPP8DPP7DPP9EPHX2 | |
| SCHEMBL21983443 | 0.78 | MEN1 (0.38) | DPP4MEN1ALDH1A1KMT2A | |
| SCHEMBL2603237 | 0.76 | MEN1 (0.47) | DPP4DPP8DPP7DPP9CHRNB2 | |
| SCHEMBL18513691 | 0.74 | FAAH (0.48) | DPP8DPP7CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22803237 | 0.73 | — | — | |
| SCHEMBL16999004 | 0.73 | CHRNB2 (0.46) | DPP4DPP8DPP7DPP9CHRNB2 | |
| SCHEMBL14018492 | 0.73 | MEN1 (0.44) | DPP4DPP8DPP7DPP9CHRNB2 | |
| SCHEMBL19419468 | 0.73 | MEN1 (0.48) | DPP4DPP8DPP9CHRNB2CHRNA3 | |
| SCHEMBL19473332 | 0.73 | MEN1 (0.44) | DPP4DPP8DPP7DPP9CHRNB2 | |
| SCHEMBL18074021 | 0.73 | CHRNB2 (0.46) | DPP4DPP8DPP7DPP9CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100282-A1 | FURO-AND THIENO[3,2-C] PYRIDINES | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |