Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 9/20 | 0.48 |
| ▸ | CA1 | P00915 | 9/20 | 0.48 |
| ▸ | CA9 | Q16790 | 9/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14703079 | 0.79 | RARB (0.53) | CA2SMN1; SMN2CA1RARBKDM4E | |
| SCHEMBL7337943 | 0.79 | CA2 (0.41) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL6955062 | 0.79 | CA2 (0.41) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL13743183 | 0.76 | CA2 (0.56) | CA2CA12CA1CA9RAB9A | |
| SCHEMBL2089792 | 0.75 | CA2 (0.52) | CA2CA12CA1CA9CHEK1 | |
| SCHEMBL18122304 | 0.74 | CA2 (0.89) | CA2SMN1; SMN2CA12CA1CA9 | |
| SCHEMBL16706013 | 0.74 | HSD11B1 (0.49) | CA2SMN1; SMN2CA1RARBKDM4E | |
| SCHEMBL6418801 | 0.74 | HSD17B10 (0.55) | SMN1; SMN2RARBKDM4ERAB9ALMNA | |
| SCHEMBL2466020 | 0.74 | HSD17B10 (0.55) | SMN1; SMN2RARBKDM4ERAB9ALMNA | |
| SCHEMBL23254983 | 0.73 | APP (0.57) | CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096198-A1 | NOVEL BIARYL DERIVATIVE | PHARMA IP LIMITED LIABILITY INTERMEDIARY CORPORATIONS (JP) | 2009-08-06 | — | — | WO | disclosed |