Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 9/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 9/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22872105 | 0.98 | ENPP1 (0.39) | ENPP1HSD17B1HSD17B2CYP3A4CYP2D6 | |
| SCHEMBL22872106 | 0.82 | HSD17B1 (0.37) | ENPP1HSD17B1HSD17B2CYP3A4CYP2D6 | |
| SCHEMBL10332125 | 0.82 | HSD17B1 (0.40) | HSD17B1HSD17B2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL22872123 | 0.81 | PDE3B (0.37) | ENPP1CYP3A4CYP2C19DAOHDAC6 | |
| SCHEMBL22872114 | 0.80 | CYP11B1 (0.37) | ENPP1HSD17B1HSD17B2CYP3A4CYP2D6 | |
| SCHEMBL18954357 | 0.80 | IKBKB (0.44) | HSD17B1HSD17B2DAOESRRGHDAC6 | |
| SCHEMBL14703090 | 0.80 | KIF11 (0.43) | HSD17B1HSD17B2APPESR1ESR2 | |
| SCHEMBL22872125 | 0.79 | ESR1 (0.40) | ENPP1HSD17B1HSD17B2CYP3A4CYP2D6 | |
| SCHEMBL14703088 | 0.78 | KIF11 (0.42) | HSD17B1HSD17B2APPESR1ESR2 | |
| SCHEMBL22872137 | 0.78 | PTPN1 (0.38) | HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279565-A2 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2023-11-22 | — | — | EP | disclosed |
| EP-3763802-B1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2023-09-06 | — | — | EP | disclosed |
| US-11168255-B2 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-11-09 | — | — | US | disclosed |
| US-20210139779-A1 | Thiophene compound, liquid-crystalline medium and liquid-crystal display comprising the same | MERCK PATENT GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
| EP-3763802-A1 | THIOPHENE COMPOUND, LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME | Merck Patent GmbH (DE) | 2021-01-13 | — | — | EP | disclosed |
| WO-2009096198-A1 | NOVEL BIARYL DERIVATIVE | PHARMA IP LIMITED LIABILITY INTERMEDIARY CORPORATIONS (JP) | 2009-08-06 | — | — | WO | disclosed |