Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.61 |
| ▸ | CA9 | Q16790 | 16/20 | 0.61 |
| ▸ | CA12 | O43570 | 15/20 | 0.61 |
| ▸ | CA1 | P00915 | 13/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA5A | P35218 | 2/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.48 |
| ▸ | VRK2 | Q86Y07 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2643602 | 0.84 | KDM4E (0.67) | CA2CA9CA12CA1CA14 | |
| SCHEMBL4488979 | 0.83 | MAP4K4 (0.54) | KDM4EMKNK1MKNK2PIK3CD | |
| SCHEMBL30337416 | 0.81 | PIK3CD (0.70) | KDM4EMKNK1MKNK2PIK3CD | |
| SCHEMBL12077575 | 0.80 | GAA (0.52) | KDM4EMKNK1MKNK2PIK3CD | |
| SCHEMBL29740321 | 0.78 | PIK3CD (0.73) | KDM4EMKNK1MKNK2PIK3CD | |
| SCHEMBL1257460 | 0.78 | PIK3CD (0.73) | KDM4EMKNK1MKNK2PIK3CD | |
| SCHEMBL17680465 | 0.77 | CA2 (0.55) | CA2CA9CA12CA1CA14 | |
| SCHEMBL12138122 | 0.75 | IKBKB (0.46) | CA2CA9CA12CA1CA14 | |
| SCHEMBL1422276 | 0.75 | CA2 (0.72) | CA2CA9CA12CA1CA14 | |
| SCHEMBL2496721 | 0.74 | CA2 (1.00) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009096198-A1 | NOVEL BIARYL DERIVATIVE | PHARMA IP LIMITED LIABILITY INTERMEDIARY CORPORATIONS (JP) | 2009-08-06 | — | — | WO | disclosed |