SCHEMBL1374423

SCHEMBL1374423

CC(=O)c1cccc(I)c1C(C)=O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
BRPF1 P55201 1/20 0.38
PBRM1 Q86U86 1/20 0.37
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HPGD P15428 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29978292 1.00 THRB (0.46) THRBKMT2AMEN1TDP1BRPF1
SCHEMBL22991414 0.86 THRB (0.54) THRBKMT2AMEN1BRPF1SMN1; SMN2
SCHEMBL600052 0.84 THRB (0.56) THRBKMT2AMEN1BRPF1PBRM1
SCHEMBL28879922 0.80 KMT2A (0.42) THRBKMT2AMEN1TDP1BRPF1
SCHEMBL6061552 0.80 THRB (0.43) THRBKMT2AMEN1TDP1BRPF1
SCHEMBL1667181 0.79 THRB (0.52) THRBKMT2AMEN1BRPF1KDM4E
SCHEMBL647863 0.79 MEN1 (0.55) KMT2AMEN1TDP1PBRM1KDM4E
SCHEMBL29457964 0.79 MEN1 (0.55) KMT2AMEN1TDP1PBRM1KDM4E
SCHEMBL19834671 0.78 BRPF1 (0.42) THRBKMT2AMEN1TDP1BRPF1
SCHEMBL7171485 0.78 THRB (0.71) THRBKMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113307781-B Synthesis method of 1,2, 3-thiadiazole derivative 新疆大学 2024-07-02 CN claimed
CN-117945980-A Isoindole thioimine compound, preparation thereof and application thereof as sigma-2 receptor inhibitor 上海健康医学院 2024-04-30 CN claimed
CN-116947699-A Iodonium salt compound with biphenyl structure, and preparation method and application thereof 同济大学 2023-10-27 CN claimed
CN-112851704-B Metal-organic framework with fluorescence amplification detection effect, preparation method thereof and application thereof in tert-butylhydroquinone detection 武汉大学 2021-12-21 CN claimed
CN-112851704-A Metal-organic framework with fluorescence amplification detection effect, preparation method thereof and application thereof in tert-butylhydroquinone detection 武汉大学 2021-05-28 CN claimed
CN-102796107-B A kind of method of synthesis pyrroles [2,3-b] Benzazole compounds KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) 2015-09-16 CN claimed
CN-103788160-A (2R,5R)-5-phosphoryl methoxy-2-(2-substituted adenine-9-yl)-2,5-dihydrofuran nucleoside analog as well as preparation method and application thereof UNIV ZHENGZHOU 2014-05-14 CN claimed
CN-102234240-B Method for synthesizing L-BMAA (Beta-Methylamino L-Alanine) hydrochloride CHEMFUTURE PHARMATECH JIANGSU LTD 2014-04-09 CN claimed
CN-102459356-B Polymerization initiator for living radical polymerization UNIV KYOTO 2013-06-12 CN claimed
CN-102796107-A Method for synthesizing pyrrol[2,3-b]indole compounds KUNMING INST BOTANY CN ACAD 2012-11-28 CN claimed
CN-102459356-A Polymerization initiator for living radical polymerization UNIV KYOTO 2012-05-16 CN claimed
CN-102234240-A Method for synthesizing L-BMAA (Beta-Methylamino L-Alanine) hydrochloride CHEMFUTURE PHARMATECH JIANGSU LTD 2011-11-09 CN claimed
CN-101481345-A Spirocyclic-beta-lactam 1-alkyl-2,7- dioxo-1- azaspiro [3.5]- nonane-5,8-diene-3-substituted carboxylic ether and preparation thereof UNIV YUNNAN (CN) 2009-07-15 CN claimed
CN-1321100-C Cation light initiator hydroxy alkoxy substituted diphenyl iodine onium salt and its preparation method UNIV JIANGNAN (CN) 2007-06-13 CN claimed
CN-1724497-A Cation light initiator hydroxy alkoxy substituted diphenyl iodine onium salt and its preparation method UNIV JIANGNAN (CN) 2006-01-25 CN claimed
CN-1425657-A Olefine epoxidation method in ionic liquid LANZHOU CHEM PHYS INST (CN) 2003-06-25 CN claimed
EP-3474890-B1 PNEUMOCOCCAL POLYSACCHARIDE-PROTEIN CONJUGATE COMPOSITION MAX PLANCK GESELLSCHAFT (DE) 2026-05-06 EP disclosed
EP-4729073-A1 SYNTHETIC VACCINES AGAINST FRANCISELLA TULARENSIS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-04-22 EP disclosed
CN-1425657-A Olefine epoxidation method in ionic liquid LANZHOU CHEM PHYS INST (CN) 2003-06-25 CN disclosed
US-5929252-A Aziridination of olefins THE SCRIPPS RESEARCH INSTITUTE (US) 1999-07-27 US disclosed