Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.52 |
| ▸ | TUBB | P07437 | 6/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.52 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.52 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.52 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507249 | 0.84 | AKR1C2 (0.53) | AKR1C2MEN1POLBKMT2ATSHR | |
| SCHEMBL15286194 | 0.82 | ABCB1 (0.65) | AKR1C2MEN1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL13744294 | 0.82 | AKR1C2 (0.76) | AKR1C2MEN1POLBKMT2ATUBB4A | |
| SCHEMBL13744802 | 0.80 | AKR1C2 (0.56) | AKR1C2MEN1POLBKMT2ATUBB4A | |
| SCHEMBL27176084 | 0.77 | AKR1C2 (0.55) | AKR1C2MEN1POLBKMT2ATUBB4A | |
| SCHEMBL27176083 | 0.77 | AKR1C2 (0.55) | AKR1C2MEN1POLBKMT2ATUBB4A | |
| SCHEMBL30267445 | 0.77 | AKR1C2 (0.55) | AKR1C2MEN1POLBKMT2ATUBB4A | |
| SCHEMBL599335 | 0.77 | AKR1C1 (0.49) | AKR1C2MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL599334 | 0.77 | AKR1C1 (0.49) | AKR1C2MEN1POLBKMT2AALDH1A1 | |
| SCHEMBL27873668 | 0.76 | AKR1C2 (0.51) | AKR1C2MEN1POLBKMT2ATUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215908-A1 | TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST | TLR4, TLR5, TLR1 | AKR1C2 3281/4885MEN1 4712/4885POLB 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.