SCHEMBL599334

SCHEMBL599334

Nc1ccccc1/C=C(/C(=O)O)c1cccc(/C(=C\c2ccccc2N)C(=O)O)c1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AKR1C1 Q04828 5/20 0.49
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
AKR1C2 P52895 4/20 0.40
AKR1C3 P42330 3/20 0.40
POLB P06746 1/20 0.40
PBRM1 Q86U86 1/20 0.40
PTGS2 P35354 3/20 0.39
HDAC3 O15379 1/20 0.38
MAPK1 P28482 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599335 1.00 AKR1C1 (0.49) AKR1C1KMT2AMEN1ALDH1A1ATM
Hydrochloric Acid SCHEMBL599818 0.98 AKR1C1 (0.47) AKR1C1KMT2AMEN1ALDH1A1ATM
Hydrochloric Acid SCHEMBL599819 0.98 AKR1C1 (0.47) AKR1C1KMT2AMEN1ALDH1A1ATM
SCHEMBL3771814 0.81 AKR1C3 (0.47) AKR1C1KMT2AMEN1MAPTAKR1C2
SCHEMBL2851432 0.81 AKR1C3 (0.47) AKR1C1KMT2AMEN1MAPTAKR1C2
SCHEMBL13744494 0.77 AKR1C2 (0.57) KMT2AMEN1ALDH1A1AKR1C2POLB
SCHEMBL600337 0.75 MAOB (0.55) AKR1C1KMT2AMEN1ALDH1A1ATM
SCHEMBL600336 0.75 MAOB (0.55) AKR1C1KMT2AMEN1ALDH1A1ATM
SCHEMBL433478 0.74 TP53 (0.47) TDP1GAAMAPTAKR1C3HDAC3
SCHEMBL10269478 0.73 AKR1C1 (0.68) AKR1C1KMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435566-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-08 US disclosed
US-10428220-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2019-10-01 US disclosed
EP-3233944-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-09-04 EP disclosed
EP-3234042-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-2393849-B1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2019-06-19 EP disclosed
EP-2834705-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS COMPRISING A CORE AND A RANDOM-COPOLYMER COATING MERCK PATENT GMBH (DE) 2018-12-05 EP disclosed
US-10126625-B2 Particles for electrophoretic displays comprising a core and a random-copolymer coating MERCK PATENT GMBH (DE) 2018-11-13 US disclosed
EP-2850116-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-04-18 EP disclosed
EP-2785797-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-20110310462-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-22 US disclosed
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-15 US disclosed
EP-2393850-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393851-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
EP-2393848-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS Merck Patent GmbH (DE) 2011-12-14 EP disclosed
US-20110297888-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-12-08 US disclosed
WO-2010089057-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089060-A2 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
WO-2010089058-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH, (DE) 2010-08-12 WO disclosed
WO-2010089059-A1 COLOURED PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435566-B2 Particles for electrophoretic displays RAB5IF, SELP, SELE AKR1C1 3435/4885KMT2A 4291/4885MEN1 3924/4885
US-20110306742-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS RAB5IF, IK, SELP AKR1C1 3041/4885KMT2A 4136/4885MEN1 4319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.