Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CASP6 | P55212 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4297147 | 0.82 | SNCA (0.49) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL13744377 | 0.82 | CYP1A2 (0.41) | SNCAALDH1A1HSD17B10CYP1A2KDM4E | |
| SCHEMBL13744645 | 0.78 | SNCA (0.43) | SNCAALDH1A1HSD17B10CYP1A2HTT | |
| SCHEMBL12521292 | 0.76 | SNCA (0.44) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL12829323 | 0.74 | SNCA (0.38) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL12807708 | 0.73 | SNCA (0.49) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL13196224 | 0.72 | LMNA (0.38) | ALDH1A1LMNAHTTSMN1; SMN2TDP1 | |
| SCHEMBL13744492 | 0.72 | ALDH1A1 (0.35) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL8469484 | 0.71 | ALDH1A1 (0.52) | SNCAALDH1A1CASP6CYP2C9CYP2C19 | |
| SCHEMBL4297142 | 0.71 | NT5E (0.66) | SNCAALDH1A1CASP6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572301-B2 | Fibre-reactive dyes, their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2009-08-11 | — | — | US | disclosed |
| US-20080250575-A1 | Fibre-Reactive Dyes, Their Preparation And Their Use | HUNTSMAN INTERNATIONAL LLC | 2008-10-16 | — | — | US | disclosed |