SCHEMBL13744792

SCHEMBL13744792

N#Cc1ccc(-c2ccc(-c3ccc(I)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.58
KIF11 P52732 3/20 0.52
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
CA1 P00915 1/20 0.48
CYP11B2 P19099 1/20 0.47
CYP2A6 P11509 2/20 0.46
ALDH1A1 P00352 1/20 0.46
CA3 P07451 1/20 0.46
CA6 P23280 1/20 0.46
CA14 Q9ULX7 1/20 0.46
TSHR P16473 2/20 0.43
HSD17B10 Q99714 1/20 0.42
NOTUM Q6P988 1/20 0.42
RIPK1 Q13546 1/20 0.42
PTPN5 P54829 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
ENPP2 Q13822 1/20 0.41
HDAC2 Q92769 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7467123 1.00 MMP3 (0.58) MMP3KIF11CA12CA2CA9
SCHEMBL82069 0.92
Water SCHEMBL11055485 0.86 MMP3 (0.74) MMP3KIF11CA12CA2CA9
SCHEMBL26246 0.86 MMP3 (0.74) MMP3KIF11CA12CA2CA9
SCHEMBL396846 0.86 MMP3 (0.74) MMP3KIF11CA12CA2CA9
SCHEMBL13063633 0.86 MMP3 (0.74) MMP3KIF11CA12CA2CA9
SCHEMBL29001482 0.84 CYP2A6 (0.46) MMP3KIF11CA12CA2CA9
SCHEMBL7019241 0.84 HDAC2 (0.46) MMP3KIF11CA12CA2CA9
SCHEMBL23625546 0.83 MMP3 (0.52) MMP3KIF11CA12CA2CA9
SCHEMBL18873994 0.83 MMP3 (0.41) MMP3KIF11CA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7575788-B2 functionation of polyvinyl alcohol with 4'-(11,11-diethoxy-undecyloxy)-biphenyl-4-carbonitrile (side-chain precursor) and octanal; sandwiching a liquid crystal layer between two substrates, one of which have above polymer, arranged so that said surface-director alignment layer facing liquid crystal layer ECSIBEO PPF2 AB (SE) 2009-08-18 US disclosed