SCHEMBL26246

SCHEMBL26246

N#Cc1ccc(-c2ccc(C#N)cc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.74
KIF11 P52732 3/20 0.64
CA2 P00918 3/20 0.58
CA12 O43570 2/20 0.58
CA9 Q16790 2/20 0.58
CA1 P00915 2/20 0.58
CYP2A6 P11509 2/20 0.58
ALDH1A1 P00352 1/20 0.58
CA3 P07451 1/20 0.58
CA6 P23280 1/20 0.58
CA14 Q9ULX7 1/20 0.58
CYP11B2 P19099 1/20 0.56
TSHR P16473 2/20 0.56
LOXL2 Q9Y4K0 1/20 0.50
NOTUM Q6P988 1/20 0.50
ENPP2 Q13822 1/20 0.50
HSD17B10 Q99714 1/20 0.50
PTPN5 P54829 1/20 0.48
HDAC2 Q92769 1/20 0.47
MMP2 P08253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13063633 1.00 MMP3 (0.74) MMP3KIF11CA2CA12CA9
Water SCHEMBL11055485 1.00 MMP3 (0.74) MMP3KIF11CA2CA12CA9
SCHEMBL396846 1.00 MMP3 (0.74) MMP3KIF11CA2CA12CA9
Methane SCHEMBL28372042 0.97 MMP3 (0.70) MMP3KIF11CA2CA12CA9
SCHEMBL16789941 0.91 MMP3 (0.64) MMP3KIF11CA2CA12CA9
SCHEMBL3611983 0.91 MMP3 (0.64) MMP3KIF11CA2CA12CA9
SCHEMBL45942 0.89 CA2 (0.69) MMP3KIF11CA2CA12CA9
SCHEMBL2503454 0.89 CA2 (0.69) MMP3KIF11CA2CA12CA9
Water SCHEMBL28254092 0.89 CA2 (0.69) MMP3KIF11CA2CA12CA9
Water SCHEMBL28189314 0.89 CA2 (0.69) MMP3KIF11CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119972186-A COFs-based photocatalytic material with improved structure and preparation method and application thereof 江苏科技大学 2025-05-13 CN claimed
CN-119702072-A Preparation of covalent organic framework fiber film and application of covalent organic framework fiber film in catalytic degradation of antibiotics 广东工业大学 2025-03-28 CN claimed
CN-116496496-B Preparation method of single-site catalyst based on triazine covalent framework materials (CTFs) 中国石油大学(华东) 2024-11-05 CN claimed
CN-118813043-A Organic framework-cucurbituril composite material based on covalent triazine and application thereof 南京理工大学 2024-10-22 CN claimed
CN-118599109-A Crystal CHFs polymer and preparation method thereof 河北师范大学 2024-09-06 CN claimed
CN-115106093-B Preparation method and application of metal covalent organic framework catalyst 中科澜荷(山东)新材料有限责任公司 2023-12-22 CN claimed
CN-117019222-A Preparation method of palladium-loaded triazinyl molecular heterojunction and application of palladium-loaded triazinyl molecular heterojunction in dipentene catalytic dehydrogenation 华侨大学 2023-11-10 CN claimed
CN-116496496-A Preparation method of single-site catalyst based on triazine covalent framework materials (CTFs) 中国石油大学(华东) 2023-07-28 CN claimed
WO-2023027359-A1 POROUS SOLID COMPOUND, METHOD FOR PREPARING SAME, CATHODE FOR LITHIUM SECONDARY BATTERY COMPRISING POROUS SOLID COMPOUND, AND LITHIUM SECONDARY BATTERY 주식회사 엘지에너지솔루션 2023-03-02 WO claimed
CN-115106093-A Preparation method and application of metal covalent organic framework catalyst 中科澜荷(山东)新材料有限责任公司 2022-09-27 CN claimed
EP-3515898-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2019-07-31 EP claimed
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2019-07-18 US claimed
WO-2018111777-A1 PORE SIZE ENGINEERING OF POROUS CARBONACEOUS MATERIALS USING COVALENT ORGANIC FRAMEWORKS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-06-21 WO claimed
WO-2018050555-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES BASF SE (DE) 2018-03-22 WO claimed
WO-2016205405-A1 COORDINATION POLYMER NDSU RESEARCH FOUNDATION (US) 2016-12-22 WO claimed
EP-2382241-B1 POLYMERS FUNCTIONALIZED WITH POLYCYANO COMPOUNDS BRIDGESTONE CORP (JP) 2016-11-23 EP claimed
EP-2456555-A1 METHOD FOR OXIDIZING METHANE Studiengesellschaft Kohle MbH (DE) 2012-05-30 EP claimed
US-20120130071-A1 METHOD FOR OXIDIZING METHANE STUDIENGESELLSCHAFT KOHLE MBH (DE) 2012-05-24 US claimed
WO-2011009429-A1 METHOD FOR OXIDIZING METHANE STUDIENGESELLSCHAFT KOHLE MBH (DE) 2011-01-27 WO claimed
US-4448940-A POLYOXAZOLINES BASED ON DINITRILES AND DIEPOXY COMPOUNDS; POLYISOCYANURATE; FLEXIBILITY; PRINTED CIRCUITS HITACHI, LTD. (JP) 1984-05-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130071-A1 METHOD FOR OXIDIZING METHANE TST, MGMT, PMS2 MMP3 3998/4885KIF11 1664/4885CA2 133/4885
US-20190218341-A1 METHOD FOR THE PREPARATION OF POLYAMINES FROM DINITRILES AND/OR AMINO NITRILES SRM, PRMT1, HNMT MMP3 4596/4885KIF11 3836/4885CA2 1591/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.