Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790150 | 0.78 | GBA1 (0.50) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16254136 | 0.76 | GBA1 (0.43) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL6518428 | 0.76 | GBA1 (0.43) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14000935 | 0.74 | GBA1 (0.46) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL5015287 | 0.74 | GBA1 (0.71) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16254169 | 0.73 | GBA1 (0.42) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14000859 | 0.72 | GBA1 (0.68) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL14501841 | 0.72 | GBA1 (0.75) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL19479651 | 0.72 | GBA1 (0.75) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL19479653 | 0.72 | GBA1 (0.68) | GBA1ADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170152234-A1 | COMPOSITIONS AND METHODS FOR QUADRICYCLANE MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-06-01 | — | — | US | disclosed |
| US-9556195-B2 | Compositions and methods for quadricyclane modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-01-31 | — | — | US | disclosed |
| US-7572939-B2 | Type of soluble pentacene precursor | ACADEMIA SINICA (TW) | 2009-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152234-A1 | COMPOSITIONS AND METHODS FOR QUADRICYCLANE MODIFICATION OF BIOMOLECULES | MYLK2, TOP2A, PYGM | GBA1 1719/4885ADRB2 2693/4885ADRB1 3698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.