Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14209963 | 0.85 | GBA1 (0.52) | GBA1ADRB2ADRB1ADRB3PPARG | |
| SCHEMBL13226121 | 0.79 | GBA1 (0.46) | GBA1PPARGPPARDPPARATSHR | |
| SCHEMBL6518428 | 0.78 | GBA1 (0.43) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL13744808 | 0.76 | GBA1 (0.46) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16977020 | 0.75 | GBA1 (0.34) | GBA1ADRB2ADRB1ADRB3PPARG | |
| SCHEMBL11790150 | 0.74 | GBA1 (0.50) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL22738801 | 0.73 | GBA1 (0.30) | GBA1 | |
| SCHEMBL16254169 | 0.70 | GBA1 (0.42) | GBA1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL16254144 | 0.70 | — | — | |
| SCHEMBL6519982 | 0.70 | GBA1 (0.52) | GBA1TSHRCYP3A4ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676676-B2 | Selective olefin metathesis with cyclometalated ruthenium complexes | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2017-06-13 | — | — | US | disclosed |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-06-30 | — | — | US | disclosed |
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-04-14 | — | — | US | disclosed |
| WO-2014201300-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | TRUSTEES OF BOSTON COLLEGE | 2014-12-18 | — | — | US | disclosed |
| WO-2014186631-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160101414-A1 | HIGHLY Z-SELECTIVE AND ENANTIOSELECTIVE RING OPENING/CROSS METATHESIS CATALYZED BY A RESOLVED STEREOGENIC-AT-RU COMPLEX | ZFR, ZDHHC7, ORC3 | GBA1 3130/4885ADRB2 850/4885ADRB1 1113/4885 |
| US-20140371454-A1 | CATALYSTS FOR EFFICIENT Z-SELECTIVE METATHESIS | ADH5, ADH1A, ADH1C | GBA1 2478/4885ADRB2 758/4885ADRB1 821/4885 |
| US-20160185684-A1 | SELECTIVE OLEFIN METATHESIS WITH CYCLOMETALATED RUTHENIUM COMPLEXES | ZDHHC7, COASY, ZDHHC2 | GBA1 1335/4885ADRB2 986/4885ADRB1 1291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.