SCHEMBL13745240

SCHEMBL13745240

CN1C(=O)N2[C@@H](Cc3ccc(O)cc3)C(=O)N(CCc3ccc(F)cc3)C[C@@H]2N1C(=O)NCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CTNNB1 P35222 2/20 0.48
▸ TCF7 P36402 2/20 0.48
▸ BCL9 O00512 1/20 0.48
▸ TCF4 P15884 1/20 0.48
▸ CLPP Q16740 1/20 0.48
▸ CREBBP Q92793 1/20 0.48
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ CYP3A4 P08684 15/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL746178 0.89 CYP3A4 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL749116 0.89 CYP3A4 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL12037711 0.87 CYP3A4 (0.55) CYP3A4
SCHEMBL13745611 0.85 CTNNB1 (0.48) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL13745456 0.85 MEN1 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL749217 0.85 MEN1 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL750070 0.85 MEN1 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL747490 0.85 MEN1 (0.51) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL747421 0.84 CYP3A4 (0.50) CTNNB1TCF7BCL9TCF4CLPP
SCHEMBL748630 0.84 CYP3A4 (0.54) CTNNB1TCF7BCL9TCF4CLPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION CHOONGWAE PHARMA CORPORATION (KR) 2009-08-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090215783-A1 COMPOSITION FOR INDUCTION OR INHIBITION OF STEM CELL DIFFERENTIATION MYLK2, TNNC1, MYH2 CTNNB1 966/4885TCF7 220/4885BCL9 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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