Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2942156 | 0.98 | HRH3 (0.41) | HRH3KCNH2MAPTCYP2D6ITGB3 | |
| SCHEMBL13515798 | 0.86 | MAPT (0.40) | MAPTITGB3ITGA2BF2RACE | |
| SCHEMBL13282365 | 0.85 | HRH3 (0.41) | HRH3KCNH2CYP2D6ALDH1A1HTR4 | |
| SCHEMBL13254062 | 0.84 | HRH3 (0.40) | HRH3KCNH2CYP2D6ALDH1A1HTR4 | |
| SCHEMBL1261174 | 0.81 | HRH3 (0.44) | HRH3KCNH2CYP2D6ITGB3ITGA2B | |
| SCHEMBL13515791 | 0.81 | SMN1; SMN2 (0.40) | HRH3KCNH2CYP2D6ALDH1A1HTR4 | |
| SCHEMBL25122685 | 0.80 | HRH3 (0.50) | HRH3KCNH2CYP2D6HTR4 | |
| Hydrochloric Acid SCHEMBL2942000 | 0.79 | HRH3 (0.43) | HRH3KCNH2CYP2D6ITGB3ITGA2B | |
| SCHEMBL19992870 | 0.79 | HTR4 (0.41) | HRH3KCNH2CYP2D6ALDH1A1HTR4 | |
| SCHEMBL13999390 | 0.79 | HRH3 (0.39) | HRH3KCNH2MAPTCYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10183944-B2 | Pyrimido-pyridazinone compounds and methods of use thereof | ASANA BIOSCIENCES, LLC (US) | 2019-01-22 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| US-20090209511-A1 | Benzofuran Derivatives | KAWAGUCHI TAKAYUKI | 2009-08-20 | — | — | US | disclosed |
| CN-100345853-C | Pyrazolopyrimidine compound and method for producing the same | TANABE SEIYAKU CO (JP) | 2007-10-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183944-B2 | Pyrimido-pyridazinone compounds and methods of use thereof | THPO, TYMP, TYMS | HRH3 866/4885KCNH2 2093/4885MAPT 4490/4885 |
| US-20090209511-A1 | Benzofuran Derivatives | F12, F2, F3 | HRH3 689/4885KCNH2 1056/4885MAPT 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.