Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261174 | 0.82 | HRH3 (0.44) | HRH3KCNH2ALDH1A1CYP2D6 | |
| SCHEMBL19993003 | 0.80 | NCF1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL2942000 | 0.80 | HRH3 (0.43) | HRH3KCNH2ALDH1A1CYP2D6 | |
| SCHEMBL13745268 | 0.79 | HRH3 (0.42) | HTR4HRH3KCNH2ALDH1A1CYP2D6 | |
| SCHEMBL20466393 | 0.77 | ALDH1A1 (0.47) | HRH3KCNH2ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL2942156 | 0.77 | HRH3 (0.41) | HTR4HRH3KCNH2ALDH1A1CYP2D6 | |
| SCHEMBL12026481 | 0.77 | HTR4 (0.47) | HTR4HRH3KCNH2ALDH1A1CACNA1I | |
| SCHEMBL524625 | 0.77 | — | — | |
| SCHEMBL26306416 | 0.77 | HTR4 (0.38) | HTR4HRH3KCNH2ALDH1A1METAP2 | |
| SCHEMBL23709475 | 0.76 | HTR4 (0.46) | HTR4HRH3KCNH2ALDH1A1CACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |