Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.61 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.61 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24098152 | 0.95 | GNAI3 (0.68) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL22340815 | 0.93 | GNAI3 (0.70) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL12021613 | 0.89 | KDM4E (0.55) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL13745554 | 0.88 | GNAI3 (0.53) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL3436777 | 0.86 | GNAI3 (0.50) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL1679331 | 0.85 | NAAA (0.70) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL15624788 | 0.85 | GNAI3 (0.59) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL13368228 | 0.85 | GNAI3 (0.52) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL14818931 | 0.85 | GNAI3 (0.52) | GAAGNAI3GNAO1GNAI1NAAA | |
| SCHEMBL13745660 | 0.84 | TSHR (0.72) | GAAGNAI3GNAO1GNAI1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098282-A1 | LOW MOLECULAR WEIGHT 2,5-DISUBSTITUTED THIOPHENE DERIVATIVES AND USE THEREOF IN THERAPY | NOVASAID AB (SE) | 2009-08-13 | — | — | WO | disclosed |