Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 6/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 3/20 | 0.34 |
| ▸ | RXRG | P48443 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 3/20 | 0.34 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARG | P13631 | 3/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745116 | 0.87 | RXRA (0.64) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13843162 | 0.81 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL14068123 | 0.81 | RXRA (0.49) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13717021 | 0.79 | RXRA (0.78) | RXRARXRBRXRGRARARARB | |
| SCHEMBL14068124 | 0.74 | RXRA (0.43) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13716956 | 0.74 | RXRA (0.52) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13745515 | 0.73 | RXRA (0.43) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13717112 | 0.73 | RXRA (0.43) | RXRAALDH1A1 | |
| SCHEMBL13717403 | 0.73 | MGLL (0.43) | RXRARXRBRXRGRARARARB | |
| SCHEMBL13717284 | 0.72 | RXRA (0.42) | RXRARXRBRXRGRARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572816-B2 | Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders | AUSPEX PHARMACEUTICALS, INC. (US) | 2009-08-11 | — | — | US | disclosed |