Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345701 | 1.00 | GAA (0.38) | GAALMNAAOC3ALDH1A1TYMP | |
| SCHEMBL12323568 | 0.82 | LMNA (0.34) | LMNAALDH1A1TYMP | |
| SCHEMBL10305069 | 0.81 | LMNA (0.33) | LMNAALDH1A1TYMP | |
| SCHEMBL17703490 | 0.81 | LMNA (0.33) | LMNAALDH1A1TYMP | |
| SCHEMBL17823732 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1TYMP | |
| SCHEMBL21056824 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1TYMP | |
| SCHEMBL17020136 | 0.79 | LMNA (0.33) | LMNAALDH1A1TYMP | |
| SCHEMBL17823959 | 0.79 | ALDH1A1 (0.38) | LMNAALDH1A1TYMP | |
| SCHEMBL24722768 | 0.78 | GAA (0.40) | GAAAOC3 | |
| SCHEMBL10304883 | 0.76 | LMNA (0.44) | LMNATYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097578-A1 | OXIM DERIVATIVES AS HSP90 INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-08-06 | — | — | WO | disclosed |