Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745443 | 0.93 | MEN1 (0.33) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13746408 | 0.77 | MEN1 (0.32) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13746202 | 0.76 | ALDH1A1 (0.31) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13746203 | 0.73 | MEN1 (0.40) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13746321 | 0.71 | MEN1 (0.38) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13745452 | 0.71 | HRH3 (0.34) | MEN1MAPTKMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL13745460 | 0.71 | HSD17B10 (0.31) | — | |
| SCHEMBL180821 | 0.69 | HRH4 (0.31) | — | |
| SCHEMBL2926247 | 0.69 | SMN1; SMN2 (0.45) | MEN1APAF1NPC1PLA2G1BHSP90AA1 | |
| SCHEMBL13745297 | 0.69 | BBOX1 (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009098257-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING AT LEAST ONE CATIONIC DIAMINO-N,N-DIHYDROPYRAZOLONE DERIVATIVE | L'OREAL (FR) | 2009-08-13 | — | — | WO | disclosed |