Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | PRCP | P42785 | 1/20 | 0.55 |
| ▸ | KLK7 | P49862 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5494817 | 1.00 | KMT2A (0.58) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL30689109 | 0.89 | CMA1 (0.56) | KMT2AMEN1PRCPKLK7NPSR1 | |
| SCHEMBL31420576 | 0.88 | PRCP (0.58) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL17335864 | 0.88 | PRCP (0.63) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL18875499 | 0.88 | PRCP (0.63) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL5964139 | 0.88 | CMA1 (0.48) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL5964142 | 0.88 | CMA1 (0.48) | KMT2AMEN1PRCPKLK7SMN1; SMN2 | |
| SCHEMBL5248179 | 0.87 | KLK7 (0.56) | KMT2AMEN1KLK7NPSR1ALDH1A1 | |
| SCHEMBL11033240 | 0.87 | HTT (0.53) | KMT2AMEN1SMN1; SMN2HTTCMA1 | |
| SCHEMBL4228972 | 0.86 | KMT2A (0.59) | KMT2AMEN1PRCPKLK7NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100360-A1 | STABILIZATION OF THE COLLAGEN TRIPLE HELIX BY O-METHYLATION OF HYDROXYPROLINE RESIDUES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-08-13 | — | — | WO | disclosed |