Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5493243 | 0.91 | HTT (0.48) | HTTMEN1KMT2AABCB1HDAC8 | |
| SCHEMBL13062784 | 0.89 | HTT (0.49) | HTTMEN1KMT2AABCB1POLB | |
| SCHEMBL3778450 | 0.89 | HTT (0.49) | HTTMEN1KMT2AABCB1POLB | |
| SCHEMBL13745767 | 0.87 | KMT2A (0.58) | HTTMEN1KMT2ACMA1FKBP1A | |
| SCHEMBL5494817 | 0.87 | KMT2A (0.58) | HTTMEN1KMT2ACMA1FKBP1A | |
| SCHEMBL17896181 | 0.83 | FKBP1A (0.51) | ABCB1FKBP1APDK1PDK2PDK3 | |
| SCHEMBL17893034 | 0.83 | FKBP1A (0.51) | ABCB1FKBP1APDK1PDK2PDK3 | |
| SCHEMBL8332542 | 0.83 | FKBP1A (0.51) | ABCB1FKBP1APDK1PDK2PDK3 | |
| SCHEMBL28974731 | 0.82 | HTT (0.62) | HTTMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28974730 | 0.82 | HTT (0.62) | HTTMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59067259-A | — | — | None | — | — | JP | disclosed |
| JP-S5967259-A | PREPARATION OF N-CONTAINING 3- OR 5-MEMBERED CYCLIC COMPOUND | OKAWA KENJI | 1984-04-16 | — | — | JP | disclosed |