SCHEMBL5494817

SCHEMBL5494817

CC(C)(C)OC(=O)N1CCC[C@H]1C(=O)NCC(=O)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.58
MEN1 O00255 1/20 0.58
PRCP P42785 1/20 0.55
KLK7 P49862 1/20 0.55
SMN1; SMN2 Q16637 2/20 0.54
HTT P42858 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
ALDH1A1 P00352 1/20 0.54
CMA1 P23946 1/20 0.54
TSHR P16473 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
CYP2C9 P11712 1/20 0.53
RAB9A P51151 1/20 0.53
CTRB1 P17538 1/20 0.52
GFER P55789 1/20 0.52
NPC1 O15118 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13745767 1.00 KMT2A (0.58) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL30689109 0.89 CMA1 (0.56) KMT2AMEN1PRCPKLK7NPSR1
SCHEMBL31420576 0.88 PRCP (0.58) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL17335864 0.88 PRCP (0.63) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL18875499 0.88 PRCP (0.63) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL5964139 0.88 CMA1 (0.48) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL5964142 0.88 CMA1 (0.48) KMT2AMEN1PRCPKLK7SMN1; SMN2
SCHEMBL5248179 0.87 KLK7 (0.56) KMT2AMEN1KLK7NPSR1ALDH1A1
SCHEMBL11033240 0.87 HTT (0.53) KMT2AMEN1SMN1; SMN2HTTCMA1
SCHEMBL4228972 0.86 KMT2A (0.59) KMT2AMEN1PRCPKLK7NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN claimed
CN-118684727-A GPRP series peptide modified dabigatran derivative, synthesis, activity and application thereof 首都医科大学 2024-09-24 CN disclosed
US-20230159622-A1 COLLAGEN MIMICS WISCONSIN ALUMNI RESEARCH FOUNDATION 2023-05-25 US disclosed
US-11390662-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2022-07-19 US disclosed
US-10329341-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2019-06-25 US disclosed
US-20180030115-A1 COLLAGEN MIMICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2018-02-01 US disclosed
US-9758569-B2 Collagen mimics WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2017-09-12 US disclosed
US-20070275897-A1 Collagen mimics NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-11-29 US disclosed