Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CD69 | Q07108 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 6/20 | 0.34 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745065 | 0.88 | ESR1 (0.54) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL14612261 | 0.88 | NOD2 (0.81) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL29366690 | 0.88 | NOD2 (0.81) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745063 | 0.82 | ESR1 (0.47) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745191 | 0.82 | ESR1 (0.47) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745082 | 0.82 | ESR1 (0.51) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745924 | 0.81 | ESR1 (0.49) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745141 | 0.79 | ESR1 (0.46) | NOD2ESR1PGRHTR1AADORA3 | |
| SCHEMBL13745076 | 0.79 | ESR1 (0.48) | NOD2ESR1PGRHTR1AADORA3 | |
| Muramyldipeptide SCHEMBL9231355 | 0.78 | NOD2 (1.00) | NOD2ESR1PGRHTR1AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214598-A1 | Monovalent and polyvalent synthetic polysaccharide antigens for immunological intervention in disease | ELI LILLY AND COMPANY (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214598-A1 | Monovalent and polyvalent synthetic polysaccharide antigens for immunological intervention in disease | CD4, TLR2, CD69 | NOD2 37/4885ESR1 3589/4885PGR 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.