Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | IGF2R | P11717 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.35 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MDK | P21741 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13745082 | 0.95 | ESR1 (0.51) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13745076 | 0.93 | ESR1 (0.48) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13745077 | 0.88 | ESR1 (0.45) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13594761 | 0.84 | ESR1 (0.54) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13745065 | 0.84 | ESR1 (0.54) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL67098 | 0.83 | ESR1 (0.60) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL12985135 | 0.83 | ESR1 (0.60) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL68824 | 0.83 | ESR1 (0.46) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13594759 | 0.83 | ESR1 (0.46) | ESR1PGRHTR1AADORA3AR | |
| SCHEMBL13745889 | 0.81 | NOD2 (0.63) | ESR1PGRHTR1AADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090214598-A1 | Monovalent and polyvalent synthetic polysaccharide antigens for immunological intervention in disease | ELI LILLY AND COMPANY (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090214598-A1 | Monovalent and polyvalent synthetic polysaccharide antigens for immunological intervention in disease | CD4, TLR2, CD69 | ESR1 3589/4885PGR 1493/4885HTR1A 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.