SCHEMBL137465

SCHEMBL137465

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr](Cl)(Cl)(=C(c1ccc(C)cc1)c1ccc(C)cc1)C1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
FABP1 P07148 1/20 0.31
P2RY14 Q15391 1/20 0.31
CYP1A2 P05177 2/20 0.31
MAPT P10636 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
PDCD1 Q15116 1/20 0.30
CD274 Q9NZQ7 1/20 0.30
NPC1 O15118 1/20 0.30
CYP3A4 P08684 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL138385 0.94 PDCD1 (0.32) PDCD1CD274
SCHEMBL2867541 0.90 PDCD1 (0.30) PDCD1CD274
SCHEMBL2872425 0.89 CNR2 (0.31) L3MBTL1
SCHEMBL141098 0.89 GRIN2C (0.35) MAPK1TDP1L3MBTL1MAPTNPC1
SCHEMBL137810 0.87 LMNA (0.37) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL143517 0.86 LMNA (0.36) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL142312 0.85 LMNA (0.36) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL142004 0.84 LMNA (0.35) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL141649 0.83 PDCD1 (0.33) PDCD1CD274
SCHEMBL5953310 0.82 EDNRB (0.32) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8513368-B2 Copolymer of olefin and conjugated diene, and process for producing the same MITSUI CHEMICALS, INC. (JP) 2013-08-20 US disclosed
US-20120059135-A1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. (JP) 2012-03-08 US disclosed