SCHEMBL142004

SCHEMBL142004

CCCC1=Cc2c(-c3ccccc3)cccc2C1[Zr](Cl)(Cl)(=C(c1ccccc1)c1ccc(C)cc1)C1C(CCC)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
AGTR1 P30556 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL142312 0.99 LMNA (0.36) LMNAMAPK1TDP1L3MBTL1AGTR1
SCHEMBL143669 0.94 SMN1; SMN2 (0.31)
SCHEMBL143517 0.91 LMNA (0.36) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL137810 0.90 LMNA (0.37) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL140544 0.88 CCKAR (0.33) L3MBTL1
SCHEMBL140970 0.85 PDCD1 (0.31) TDP1L3MBTL1
SCHEMBL137465 0.84 LMNA (0.36) LMNAMAPK1TDP1L3MBTL1MEN1
SCHEMBL139930 0.83 SMN1; SMN2 (0.32)
SCHEMBL138385 0.81 PDCD1 (0.32)
SCHEMBL137121 0.79 MAPT (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415792-B1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME MITSUI CHEMICALS INC (JP) 2014-11-12 EP disclosed
US-8513368-B2 Copolymer of olefin and conjugated diene, and process for producing the same MITSUI CHEMICALS, INC. (JP) 2013-08-20 US disclosed
US-20120059135-A1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. (JP) 2012-03-08 US disclosed
EP-2415792-A1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME Mitsui Chemicals, Inc. (JP) 2012-02-08 EP disclosed