Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | GPR4 | P46093 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24112497 | 0.86 | CTSD (0.46) | CTSDCTSLCTSBCTSSHPGD | |
| SCHEMBL9358174 | 0.86 | CTSD (0.66) | CTSDCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL25450670 | 0.83 | CTSD (0.44) | CTSDCTSLCTSBCTSSGPR4 | |
| SCHEMBL19200747 | 0.83 | KMT2A (0.42) | CTSDCTSLCTSBCTSSHPGD | |
| SCHEMBL3930563 | 0.82 | ITGB3 (0.47) | CTSDCTSLCTSBCTSSHPGD | |
| SCHEMBL1561382 | 0.81 | ATM (0.49) | CTSDCTSLCTSBCTSSHPGD | |
| SCHEMBL14393789 | 0.81 | CTSD (0.43) | CTSDCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL14826064 | 0.81 | ATM (0.41) | HPGDALDH1A1ATMKMT2AMEN1 | |
| SCHEMBL8245093 | 0.79 | CTSD (0.44) | CTSDCTSLCTSBCTSSALDH1A1 | |
| SCHEMBL30911353 | 0.76 | CHRM2 (0.37) | CTSDCTSLCTSBCTSSHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102325-A1 | IMIDAZOLYL BIPHENYL IMIDAZOLES AS HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2008021927-A2 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-02-21 | — | — | WO | disclosed |