Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805104 | 1.00 | CA2 (0.50) | CA2MAPK1GPR84FFAR1ACE2 | |
| SCHEMBL17527088 | 1.00 | CA2 (0.50) | CA2MAPK1GPR84FFAR1ACE2 | |
| SCHEMBL7761200 | 1.00 | CA2 (0.50) | CA2MAPK1GPR84FFAR1ACE2 | |
| SCHEMBL3680620 | 0.93 | GPR84 (0.57) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL7083484 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL2498859 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL22552585 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL22552779 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL1271078 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 | |
| SCHEMBL7075692 | 0.91 | GPR84 (0.61) | GPR84FFAR1ACE2ABCB1SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103953-A1 | TREATMENT OF ENERGY UTILIZATION DISEASE | SUMMIT CORPORATION PLC (GB) | 2009-08-27 | — | — | WO | disclosed |