Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 1.00 |
| ▸ | PGR | P06401 | 9/20 | 1.00 |
| ▸ | NR3C2 | P08235 | 7/20 | 1.00 |
| ▸ | AR | P10275 | 6/20 | 1.00 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13747742 | 1.00 | NR3C1 (1.00) | NR3C1PGRNR3C2ARREN | |
| SCHEMBL4540162 | 0.91 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4189603 | 0.91 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4204006 | 0.91 | NR3C1 (0.82) | NR3C1PGRNR3C2AR | |
| SCHEMBL4188773 | 0.90 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4186483 | 0.90 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4186486 | 0.90 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL4188377 | 0.89 | NR3C1 (1.00) | NR3C1PGRNR3C2AR | |
| SCHEMBL13747458 | 0.88 | NR3C1 (0.78) | NR3C1PGRNR3C2ARREN | |
| SCHEMBL4538515 | 0.88 | NR3C1 (0.78) | NR3C1PGRNR3C2ARREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103007-A2 | STEROID HORMONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2009-08-20 | — | — | WO | disclosed |