Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 15/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749166 | 0.79 | KDM4E (0.47) | ABCG2ABCB1LMNAMAPTNPSR1 | |
| SCHEMBL13748440 | 0.76 | MAPT (0.66) | ABCG2MAPTNPSR1MAPK1 | |
| SCHEMBL13882262 | 0.73 | ABCG2 (0.71) | ABCG2ABCB1LMNAMAPTNPSR1 | |
| SCHEMBL13882337 | 0.73 | ABCG2 (0.74) | ABCG2ABCB1LMNATP53MAPT | |
| SCHEMBL13749167 | 0.72 | MAPT (0.47) | ABCG2ABCB1LMNAMAPTNPSR1 | |
| SCHEMBL13748742 | 0.72 | TSHR (0.59) | ABCG2ABCB1LMNA | |
| SCHEMBL13882446 | 0.72 | ABCG2 (0.89) | ABCG2ABCB1LMNATP53NPSR1 | |
| SCHEMBL13882509 | 0.72 | ABCG2 (0.81) | ABCG2ABCB1LMNATP53 | |
| SCHEMBL4264083 | 0.70 | ABCG2 (1.00) | ABCG2ABCB1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL13882344 | 0.70 | LMNA (0.70) | ABCG2ABCB1LMNATP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102377-A2 | ANTIBIOTIC TETRAHYDRO-BETA-CARBOLINE DERIVATIVES | MAXTHERA INC. (US) | 2009-08-20 | — | — | WO | disclosed |