Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13749167 | 0.89 | MAPT (0.47) | KDM4EMAPTALDH1A1ABCG2MEN1 | |
| SCHEMBL13748418 | 0.79 | ABCG2 (0.57) | MAPTABCG2NPSR1ABCB1LMNA | |
| SCHEMBL2783497 | 0.74 | KDM4E (0.48) | KDM4EMAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL13749164 | 0.73 | MAPT (0.49) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13748468 | 0.72 | MAPT (0.48) | KDM4EMAPTALDH1A1ABCG2MEN1 | |
| SCHEMBL17928402 | 0.71 | ESR1 (0.69) | KDM4EMAPTALDH1A1ABCG2ESR1 | |
| SCHEMBL13748915 | 0.70 | KDM4E (0.48) | KDM4EMAPTALDH1A1ABCG2MEN1 | |
| SCHEMBL13912140 | 0.69 | ESR1 (0.60) | KDM4EMAPTALDH1A1ABCG2MEN1 | |
| SCHEMBL5527250 | 0.67 | MAPT (0.75) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2508073 | 0.67 | MAPT (0.75) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102377-A2 | ANTIBIOTIC TETRAHYDRO-BETA-CARBOLINE DERIVATIVES | MAXTHERA INC. (US) | 2009-08-20 | — | — | WO | disclosed |