SCHEMBL13748422

SCHEMBL13748422

CCN(C(=O)OC(C)(C)C)C(C)Cc1ccc2c(c1)OC(CN)O2

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.31
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4057680 0.89 SIRT2 (0.32) SLC7A5AAK1
SCHEMBL4058026 0.87 POLB (0.34) SLC7A5
SCHEMBL13748613 0.87 AAK1 (0.35) SLC7A5AAK1
SCHEMBL4068936 0.85 CYP4F2 (0.34)
SCHEMBL25311529 0.81 TAAR1 (0.47)
SCHEMBL25311533 0.81 TAAR1 (0.47)
SCHEMBL13748424 0.81 AAK1 (0.32) SLC7A5AAK1
SCHEMBL13748451 0.80 SYK (0.41)
SCHEMBL13748882 0.78 ALOX15 (0.46) SLC7A5
SCHEMBL13749303 0.78 AKT1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569676-B2 Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2009-08-04 US disclosed
EP-1498415-B1 Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs ROCHE DIAGNOSTICS GMBH (DE) 2007-06-27 EP disclosed