SCHEMBL13748424

SCHEMBL13748424

CCC(Cc1ccc2c(c1)OC(CN)O2)N(C)C(=O)OC(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.32
SLC7A5 Q01650 1/20 0.31
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13748429 0.89 SIRT2 (0.32) AAK1SLC7A5ADORA1
SCHEMBL13748613 0.87 AAK1 (0.35) AAK1SLC7A5
SCHEMBL13748626 0.85 CYP4F2 (0.34) ADORA1
SCHEMBL13748422 0.81 SLC7A5 (0.31) AAK1SLC7A5
SCHEMBL13748614 0.80 SYK (0.43)
SCHEMBL13749024 0.77 ALOX15 (0.42) SLC7A5
SCHEMBL13749099 0.77 ACHE (0.34) AAK1SLC7A5
SCHEMBL13749054 0.76 AAK1 (0.35) AAK1SLC7A5
SCHEMBL13749158 0.75 ACE (0.39)
SCHEMBL24111886 0.74 HTR1B (0.47) AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7569676-B2 Ecstasy-class derivatives, immunogens, and antibodies and their use in detecting ecstasy-class drugs ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2009-08-04 US disclosed