Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 6/20 | 0.44 |
| ▸ | GIPR | P48546 | 3/20 | 0.44 |
| ▸ | USP5 | P45974 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255802 | 0.91 | MEN1 (0.48) | GCGRGIPRUSP5ALDH1A1MEN1 | |
| SCHEMBL2251590 | 0.90 | KMT2A (0.48) | GCGRGIPRALDH1A1MEN1KMT2A | |
| SCHEMBL2667291 | 0.89 | GCGR (0.59) | GCGRGIPRUSP5CYP2C9 | |
| SCHEMBL13748634 | 0.85 | GCGR (0.46) | GCGRGIPRALDH1A1MEN1KMT2A | |
| SCHEMBL2667296 | 0.85 | GCGR (0.57) | GCGRGIPRALDH1A1 | |
| SCHEMBL2253874 | 0.85 | GCGR (0.42) | GCGRGIPRUSP5ALDH1A1MEN1 | |
| SCHEMBL13003304 | 0.84 | GCGR (0.53) | GCGRGIPRUSP5CYP2C9 | |
| SCHEMBL12360426 | 0.82 | GCGR (0.59) | GCGRGIPRUSP5CYP2C9 | |
| SCHEMBL13748622 | 0.81 | GCGR (0.47) | GCGRGIPRCYP2C9 | |
| SCHEMBL2667300 | 0.81 | GCGR (0.58) | GCGRGIPRUSP5CYP2C9TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572922-B2 | Substituted pyrazoles, compositions containing such compounds and methods of use | MERCK & CO., INC. (US) | 2009-08-11 | — | — | US | disclosed |