Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748746 | 0.95 | MAPT (0.51) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748946 | 0.94 | KIF11 (0.54) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748231 | 0.92 | KIF11 (0.51) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748728 | 0.91 | ESR1 (0.55) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748974 | 0.90 | KIF11 (0.49) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748669 | 0.90 | KIF11 (0.51) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748234 | 0.89 | KDM4E (0.60) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748191 | 0.89 | MAPT (0.45) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748197 | 0.87 | KDM4E (0.49) | KIF11MAPTKDM4EMEN1KMT2A | |
| SCHEMBL13748571 | 0.81 | KIF11 (0.52) | KIF11MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102377-A2 | ANTIBIOTIC TETRAHYDRO-BETA-CARBOLINE DERIVATIVES | MAXTHERA INC. (US) | 2009-08-20 | — | — | WO | disclosed |