Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748945 | 0.94 | KIF11 (0.54) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748728 | 0.94 | ESR1 (0.55) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748231 | 0.90 | KIF11 (0.51) | KIF11MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13748974 | 0.90 | KIF11 (0.49) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748746 | 0.90 | MAPT (0.51) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748191 | 0.88 | MAPT (0.45) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748669 | 0.86 | KIF11 (0.51) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748234 | 0.86 | KDM4E (0.60) | KIF11MAPTMEN1KMT2AKDM4E | |
| SCHEMBL13748197 | 0.85 | KDM4E (0.49) | KIF11ESR1PGRMAPTMEN1 | |
| SCHEMBL13748571 | 0.82 | KIF11 (0.52) | KIF11ESR1PGRMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009102377-A2 | ANTIBIOTIC TETRAHYDRO-BETA-CARBOLINE DERIVATIVES | MAXTHERA INC. (US) | 2009-08-20 | — | — | WO | disclosed |