Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2649233 | 0.84 | NR4A1 (0.50) | HMGB1CXCL12NR4A1NR4A2NR4A3 | |
| SCHEMBL6323290 | 0.82 | CNR2 (0.50) | HMGB1CXCL12NR4A1NR4A2NR4A3 | |
| SCHEMBL30838413 | 0.81 | NR4A1 (0.65) | HMGB1NR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL30838412 | 0.81 | NR4A1 (0.65) | HMGB1NR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL29406630 | 0.81 | NR4A1 (0.65) | HMGB1NR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL28798 | 0.81 | NR4A1 (0.65) | HMGB1NR4A1NR4A2NR4A3WDR5 | |
| SCHEMBL17537563 | 0.81 | TDP1 (0.56) | HMGB1CXCL12NR4A1NR4A2NR4A3 | |
| SCHEMBL29624842 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12NR4A1NR4A2NR4A3 | |
| SCHEMBL5500921 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12NR4A1NR4A2NR4A3 | |
| SCHEMBL926511 | 0.81 | HMGB1 (0.47) | HMGB1CXCL12NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097992-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2009-08-13 | — | — | WO | disclosed |