Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.49 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331460 | 0.87 | CNR2 (0.55) | CNR2HMGB1CXCL12NR4A3NR4A1 | |
| SCHEMBL2649233 | 0.86 | NR4A1 (0.50) | HMGB1CXCL12NR4A3NR4A1NR4A2 | |
| Butane SCHEMBL2566138 | 0.85 | NR4A3 (0.54) | HMGB1CXCL12NR4A3NR4A1NR4A2 | |
| SCHEMBL15583274 | 0.84 | CNR2 (0.50) | CNR2ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL6332056 | 0.84 | CNR2 (0.56) | CNR2HMGB1CXCL12KDM4ETSHR | |
| SCHEMBL28843982 | 0.83 | HMGB1 (0.45) | HMGB1CXCL12NR4A3NR4A1NR4A2 | |
| SCHEMBL28280851 | 0.83 | CNR2 (0.54) | CNR2 | |
| SCHEMBL28798 | 0.82 | NR4A1 (0.65) | HMGB1NR4A3NR4A1NR4A2CYP2C9 | |
| SCHEMBL30838413 | 0.82 | NR4A1 (0.65) | HMGB1NR4A3NR4A1NR4A2CYP2C9 | |
| SCHEMBL29406630 | 0.82 | NR4A1 (0.65) | HMGB1NR4A3NR4A1NR4A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117416983-A | Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method | 中国科学院青海盐湖研究所 | 2024-01-19 | — | — | CN | claimed |
| CN-116836081-A | Ether epoxy toughening agent and preparation method and application thereof | 中国林业科学研究院林产化学工业研究所 | 2023-10-03 | — | — | CN | claimed |
| CN-111440137-B | 3, 4-benzocoumarin derivative and preparation method and application thereof | 华东理工大学 | 2022-08-16 | — | — | CN | claimed |
| CN-111440137-A | 3, 4-benzocoumarin derivative and preparation method and application thereof | 华东理工大学 | 2020-07-24 | — | — | CN | claimed |
| CN-111410603-A | Benzanthrone derivative, preparation method thereof and application thereof in functional pigment | 上海甘田光学材料有限公司 | 2020-07-14 | — | — | CN | claimed |
| CN-117416983-A | Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method | 中国科学院青海盐湖研究所 | 2024-01-19 | — | — | CN | disclosed |
| CN-111410603-B | Benzanthrone derivative, preparation method thereof and application thereof in functional pigment | 上海甘田光学材料有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-111440137-B | 3, 4-benzocoumarin derivative and preparation method and application thereof | 华东理工大学 | 2022-08-16 | — | — | CN | disclosed |
| CN-111440137-A | 3, 4-benzocoumarin derivative and preparation method and application thereof | 华东理工大学 | 2020-07-24 | — | — | CN | disclosed |
| CN-111410603-A | Benzanthrone derivative, preparation method thereof and application thereof in functional pigment | 上海甘田光学材料有限公司 | 2020-07-14 | — | — | CN | disclosed |
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| US-9924716-B2 | Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto | DOW AGROSCIENCES LLC (US) | 2018-03-27 | — | — | US | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |
| US-8846760-B2 | Dihydronaphthalene and naphthalene derivatives as N-formyl peptide receptor like-1 (FPRL-1) receptor modulators | ALLERGAN, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-20140128471-A1 | DIHYDRONAPHTHALENE AND NAPHTHALENE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN, INC. (US) | 2014-05-08 | — | — | US | disclosed |
| CN-101560272-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-04-13 | — | — | CN | disclosed |
| CN-101560273-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-03-23 | — | — | CN | disclosed |
| CN-101560273-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| CN-101560272-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CLEMSON UNIVERSITY | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009903-A1 | CB2-selective cannabinoid analogues | CNR2, CNR1, GPR68 | CNR2 1/4885HMGB1 1374/4885CXCL12 1734/4885 |
| US-20140128471-A1 | DIHYDRONAPHTHALENE AND NAPHTHALENE DERIVATIVES AS N-FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | FPR1, FPR2, FPR3 | CNR2 133/4885HMGB1 411/4885CXCL12 509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.